Surgery for tardive dyskinesia.

Authors :: Thobois S
Poisson A
Damier P
Source :: International review of neurobiology [Int Rev Neurobiol] 2011; Vol. 98, pp. 289-96.
Publication Year :: 2011
Abstract: Tardive dyskinesia (TD) is an often bothersome side effect of antipsychotic treatment. Medical treatment options are usually disappointing. A few single case reports have suggested some efficacy of lesionning surgery (i.e. pallidotomy or thalamotomy). A much greater number of series (including one controlled-study) have assessed the effects of deep brain stimulation applied to the internal globus pallidus. All of them have shown a marked improvement of motor symptoms without any major psychiatric side effects.<br /> (Copyright © 2011 Elsevier Inc. All rights reserved.)