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[Guidelines for diagnosis, treatment, surveillance and prevention of cancer in patients with familial non-adenomatous polyposis].
- Source :
-
Harefuah [Harefuah] 2011 Jul; Vol. 150 (7), pp. 607-10, 615. - Publication Year :
- 2011
-
Abstract
- Approximately 30% of colorectal cancers exhibit familial clustering. Currently, we recognize a number of different types of polyps and polyposis syndromes that are classified according to the histology of the typical polyp. We differentiate between adenomas, hyperplastic, and hamartomatous polyps as well as between syndromes that are manifested by 10-100 or above 100 polyps. It is essential to distinguish between these syndromes as each has a different mode of presentation, spectrum of signs and symptoms and cancer risk associated with them. With the knowledge accumulating, we now have the tools to lower the risk of cancer by performing specific screening programs that are tailored to each syndrome. In these guidelines we focus on the non-adenomatous polyps, hyperplastic and hamartomatous polyposis syndromes. We outline the importance of multi-sector team work that includes the family practitioner, gastroenterologist, pathologist, genetic counselor, surgeon, and social worker.
- Subjects :
- Colonic Polyps diagnosis
Colonic Polyps pathology
Colorectal Neoplasms etiology
Colorectal Neoplasms pathology
Humans
Hyperplasia
Intestinal Polyposis diagnosis
Intestinal Polyposis pathology
Israel
Mass Screening methods
Patient Care Team organization & administration
Peutz-Jeghers Syndrome diagnosis
Peutz-Jeghers Syndrome pathology
Risk
Colorectal Neoplasms prevention & control
Intestinal Polyposis complications
Peutz-Jeghers Syndrome complications
Subjects
Details
- Language :
- Hebrew
- ISSN :
- 0017-7768
- Volume :
- 150
- Issue :
- 7
- Database :
- MEDLINE
- Journal :
- Harefuah
- Publication Type :
- Academic Journal
- Accession number :
- 21874774