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Complications of HIV disease and antiretroviral therapy.
- Source :
-
Topics in antiviral medicine [Top Antivir Med] 2011 May-Jun; Vol. 19 (2), pp. 58-68. - Publication Year :
- 2011
-
Abstract
- Studies on new direct-acting antivirals (DAAs) for hepatitis C virus infection were a focus of the 2011 Conference on Retroviruses and Opportunistic Infections. Although the majority of the data were from HIV-uninfected patients, much-needed work has begun to characterize DAA and antiretroviral drug interactions and to evaluate performance of DAAs for HIV/HCV-coinfected patients. There was continued emphasis on pathogenesis, management, and prevention of the long-term complications of HIV disease and its therapies, including cardiovascular disease, lipodystrophy, renal disease, and alterations in bone metabolism. Malignancies, particularly non-AIDS-defining cancers, have emerged as a leading complication and cause of death in HIV infection that may not be fully mitigated by immune reconstitution with antiretroviral therapy. This year's conference also highlighted important data on the optimal timing of antiretroviral therapy in tuberculosis coinfection, as well as the treatment and prevention of common coinfections including cryptococcal meningitis and influenza.
- Subjects :
- Hepatitis C complications
Hepatitis C drug therapy
Humans
Time Factors
Anti-HIV Agents administration & dosage
Anti-HIV Agents adverse effects
Antiretroviral Therapy, Highly Active adverse effects
Antiretroviral Therapy, Highly Active methods
HIV Infections complications
HIV Infections drug therapy
Subjects
Details
- Language :
- English
- ISSN :
- 2161-5853
- Volume :
- 19
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Topics in antiviral medicine
- Accession number :
- 21868823