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Heyde's syndrome: A critical review of the literature.
- Source :
-
The Journal of heart valve disease [J Heart Valve Dis] 2011 Jul; Vol. 20 (4), pp. 366-75. - Publication Year :
- 2011
-
Abstract
- Heyde's syndrome is an uncommon association between aortic stenosis and gastrointestinal bleeding. Although initially described during the late 1950s, with subsequent reports of a possible link between these disorders, controversy persists regarding the incidence, pathogenesis, and treatment of this syndrome. The main disagreements center on the actual association of aortic stenosis and angiodysplasia, though other controversies include the pathogenesis of Heyde's syndrome, ranging from von Willebrand factor deficiency and age-related degeneration to mucosal ischemia and cholesterol embolization. A variety of treatment modalities of the syndrome has been applied, including medical management, endoscopic therapy, embolization, and aortic valve replacement. Here, the controversies surrounding Heyde's syndrome, which focus on pathogenesis and treatment, are reviewed with the aim of providing a clearer understanding of the syndrome and the implications for patient care.
- Subjects :
- Cardiac Surgical Procedures methods
Endoscopy, Gastrointestinal methods
Humans
Incidence
Morbidity
Severity of Illness Index
Syndrome
United States epidemiology
Vascular Surgical Procedures methods
Abnormalities, Multiple
Angiodysplasia diagnosis
Angiodysplasia epidemiology
Angiodysplasia therapy
Aortic Valve Stenosis diagnosis
Aortic Valve Stenosis epidemiology
Aortic Valve Stenosis therapy
Gastrointestinal Hemorrhage diagnosis
Gastrointestinal Hemorrhage epidemiology
Gastrointestinal Hemorrhage etiology
Subjects
Details
- Language :
- English
- ISSN :
- 0966-8519
- Volume :
- 20
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- The Journal of heart valve disease
- Publication Type :
- Academic Journal
- Accession number :
- 21863647