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Structural revision of periplocosides and periperoxides, natural immunosuppressive agents from the genus Periploca.
- Source :
-
Phytochemistry [Phytochemistry] 2011 Dec; Vol. 72 (17), pp. 2230-6. Date of Electronic Publication: 2011 Aug 16. - Publication Year :
- 2011
-
Abstract
- The structures of a series of peroxy function containing pregnane glycosides isolated from Periploca sepium and Periploca forrestii were revised to be orthoester group bearing ones using 2D NMR spectroscopic techniques, as well as chemical transformations and X-ray crystallographic diffraction analysis. The orthoester function appears to be an essential structural feature for immunosuppressive activity.<br /> (Copyright © 2011 Elsevier Ltd. All rights reserved.)
- Subjects :
- Crystallography, X-Ray
Glycosides isolation & purification
Immunosuppressive Agents isolation & purification
Magnetic Resonance Spectroscopy
Molecular Structure
Peroxides isolation & purification
Glycosides chemistry
Immunosuppressive Agents chemistry
Periploca chemistry
Peroxides chemistry
Plant Extracts chemistry
Subjects
Details
- Language :
- English
- ISSN :
- 1873-3700
- Volume :
- 72
- Issue :
- 17
- Database :
- MEDLINE
- Journal :
- Phytochemistry
- Publication Type :
- Academic Journal
- Accession number :
- 21843896
- Full Text :
- https://doi.org/10.1016/j.phytochem.2011.07.018