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Pre-surgical mood predicts memory decline after anterior temporal lobe resection for epilepsy.
- Source :
-
Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists [Arch Clin Neuropsychol] 2011 Dec; Vol. 26 (8), pp. 739-45. Date of Electronic Publication: 2011 Aug 11. - Publication Year :
- 2011
-
Abstract
- This study examined pre-surgical depressed mood as a predictor of post-surgical memory change in adults who underwent temporal lobe resections (TLRs; n = 211). Patients completed the Wechsler Memory Scale-III and Beck Depression Inventory-Second Edition (BDI-II) before and after TLR (left = 110, right = 101) and were divided into two groups (clinically elevated depressive symptoms or not depressed) based on BDI-II score. Left-TLR patients with poorer pre-surgical mood had greater verbal memory declines after surgery compared with nondepressed left- or right-TLR patients and right-TLR patients with poor mood. Further, pre-surgical BDI-II score demonstrated incremental validity in predicting post-surgical memory change in left-TLR patients beyond pre-surgical memory scores. Differences in seizure outcome and post-surgical mood change could not account for memory decline. Results suggest that elevated pre-surgical depressive symptomatology is a risk factor for post-surgical memory decline and indicate that mood should be considered when advising patients about cognitive risks associated with temporal lobectomy. Results are discussed in terms of poor pre-surgical mood as an indicator of reduced cognitive reserve.
- Subjects :
- Adolescent
Adult
Aged
Analysis of Variance
Anterior Temporal Lobectomy adverse effects
Anterior Temporal Lobectomy methods
Epilepsy, Temporal Lobe surgery
Female
Humans
Male
Memory Disorders psychology
Mental Status Schedule
Middle Aged
Neuropsychological Tests
Reproducibility of Results
Retrospective Studies
Treatment Outcome
Young Adult
Affective Disorders, Psychotic complications
Anterior Temporal Lobectomy psychology
Epilepsy, Temporal Lobe psychology
Memory Disorders etiology
Preoperative Care psychology
Subjects
Details
- Language :
- English
- ISSN :
- 1873-5843
- Volume :
- 26
- Issue :
- 8
- Database :
- MEDLINE
- Journal :
- Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists
- Publication Type :
- Academic Journal
- Accession number :
- 21840873
- Full Text :
- https://doi.org/10.1093/arclin/acr067