Low relative abundances of the mucolytic bacterium Akkermansia muciniphila and Bifidobacterium spp. in feces of children with autism.

Authors :: Wang L
Christophersen CT
Sorich MJ
Gerber JP
Angley MT
Conlon MA
Source :: Applied and environmental microbiology [Appl Environ Microbiol] 2011 Sep; Vol. 77 (18), pp. 6718-21. Date of Electronic Publication: 2011 Jul 22.
Publication Year :: 2011
Abstract: Gastrointestinal disturbance is frequently reported for individuals with autism. We used quantitative real-time PCR analysis to quantify fecal bacteria that could influence gastrointestinal health in children with and without autism. Lower relative abundances of Bifidobacteria species and the mucolytic bacterium Akkermansia muciniphila were found in children with autism, the latter suggesting mucus barrier changes.

Subjects :: Bacterial Load
Bifidobacterium genetics
Child
Dyspepsia microbiology
Humans
Mucus metabolism
Real-Time Polymerase Chain Reaction
Verrucomicrobia genetics
Autistic Disorder complications
Bifidobacterium isolation & purification
Dyspepsia epidemiology
Feces microbiology
Verrucomicrobia isolation & purification

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