[Comparative study of mucosa irritation of crude and processed Radix Phytolaccae].

Authors :: Chen L
Wu H
Wang M
Shi R
Source :: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica [Zhongguo Zhong Yao Za Zhi] 2011 Apr; Vol. 36 (7), pp. 859-63.
Publication Year :: 2011
Abstract: Objective: To study the changes of mucosa irritation of crude and processed Radix Phytolaccae.<br />Method: Gastrointestinal experiments on rats and mice and the rabbits' eyes irritation experiments were applied to investigate the changes of mucosa irritation of crude and processed Radix Phytolaccae.<br />Result: The mucosa irritation of processed Radix Phytolaccae decreased obviously compared to crude one.<br />Conclusion: After being processed with vinegar, the mucosa irritation on Radix Phytolaccae decreased obviously.

Subjects :: Acetic Acid chemistry
Animals
Dinoprostone metabolism
Eye drug effects
Gastric Mucosa metabolism
Male
Mice
Rats
Drug Compounding
Drugs, Chinese Herbal adverse effects
Drugs, Chinese Herbal chemistry
Gastric Mucosa drug effects
Phytolacca chemistry
Plant Roots chemistry

Language :: Chinese
ISSN :: 1001-5302
Volume :: 36
Issue :: 7
Database :: MEDLINE
Journal :: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
Publication Type :: Academic Journal
Accession number :: 21761722

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