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Immunohistochemistrical and clinicopathological characterization of chronic endometritis.
- Source :
-
American journal of reproductive immunology (New York, N.Y. : 1989) [Am J Reprod Immunol] 2011 Nov; Vol. 66 (5), pp. 410-5. Date of Electronic Publication: 2011 Jul 12. - Publication Year :
- 2011
-
Abstract
- Problem: Chronic endometritis is an elusive entity that is often asymptomatic and undetectable by conventional endometrial biopsy and histological examination. Using immunohistochemistry for full-thickness endometrium, we sought for its clinicopathological features.<br />Method of Study: Two hundred and thirty-four archival endometrial specimens obtained by hysterectomy were immunostained for the plasmacyte marker syndecan-1 to identify chronic endometritis. Endometrial morphology was dated by the standard criteria. The immunoreactive cells were enumerated in 10 non-overlapping endometrial stromal areas. The clinical parameters were obtained from the medical charts.<br />Results: Chronic endometritis was identified in 11.1% of the samples examined. Its occurrence was similar between the proliferative phase and secretory phase. A total of 23.1% of the cases were asymptomatic. Stromal plasmacyte infiltration and morphological delay were more prominent in symptomatic chronic endometritis than in asymptomatic counterpart.<br />Conclusions: Chronic endometritis is a common gynecological pathological condition and more often asymptomatic than ever expected. There was no menstrual cycle-dependent fluctuation in its occurrence.<br /> (© 2011 John Wiley & Sons A/S.)
Details
- Language :
- English
- ISSN :
- 1600-0897
- Volume :
- 66
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- American journal of reproductive immunology (New York, N.Y. : 1989)
- Publication Type :
- Academic Journal
- Accession number :
- 21749546
- Full Text :
- https://doi.org/10.1111/j.1600-0897.2011.01051.x