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High-performance thin-layer chromatography/mass spectrometry for the analysis of neutral glycosphingolipids.

Authors :
Suzuki A
Miyazaki M
Matsuda J
Yoneshige A
Source :
Biochimica et biophysica acta [Biochim Biophys Acta] 2011 Nov; Vol. 1811 (11), pp. 861-74. Date of Electronic Publication: 2011 Jun 26.
Publication Year :
2011

Abstract

This mini-review summarizes the protocol we have developed for the analysis of neutral glycosphingolipids (GSLs) by high-performance thin layer chromatography (HPTLC)-mass spectrometry (MS). We also present results obtained using this glycolipidomic approach to study neutral GSLs from mouse kidney, spleen, and small intestine. Finally, we discuss what is required for further development of this method, as well as what is expected for the future of glycolipid biology.<br /> (Copyright © 2011 Elsevier B.V. All rights reserved.)

Details

Language :
English
ISSN :
0006-3002
Volume :
1811
Issue :
11
Database :
MEDLINE
Journal :
Biochimica et biophysica acta
Publication Type :
Academic Journal
Accession number :
21740982
Full Text :
https://doi.org/10.1016/j.bbalip.2011.06.018