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[Management of anal canal carcinoma].
- Source :
-
Revue medicale suisse [Rev Med Suisse] 2011 May 25; Vol. 7 (296), pp. 1144-8. - Publication Year :
- 2011
-
Abstract
- Although anal canal squamous cell carcinoma is rare, the general practitioner should consider this diagnosis in a patient with persistent lower abdominal symptoms. While classically observed in older women, an increased incidence is also seen in HIV-positive patients or patients with a history of human papillomavirus infection. Initial diagnosis and local work-up require assessment by a proctologist. Standard curative treatment combines radiotherapy with 5-FU- and MMC-based chemotherapy. Salvage surgery should be discussed in case of local relapse. The general practitioner, the proctologist and the radiation oncologist, all participate in post-treatment surveillance.
- Subjects :
- Anal Canal pathology
Anus Neoplasms epidemiology
Anus Neoplasms pathology
Anus Neoplasms virology
Carcinoma, Squamous Cell epidemiology
Carcinoma, Squamous Cell pathology
Carcinoma, Squamous Cell virology
Combined Modality Therapy methods
Fluorouracil administration & dosage
HIV Seropositivity complications
Humans
Incidence
Mitomycin administration & dosage
Risk Factors
Salvage Therapy methods
Sex Distribution
Surgical Procedures, Operative
Treatment Outcome
Antineoplastic Combined Chemotherapy Protocols therapeutic use
Anus Neoplasms therapy
Carcinoma, Squamous Cell therapy
Subjects
Details
- Language :
- French
- ISSN :
- 1660-9379
- Volume :
- 7
- Issue :
- 296
- Database :
- MEDLINE
- Journal :
- Revue medicale suisse
- Publication Type :
- Academic Journal
- Accession number :
- 21721205