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Hemangiopericytoma-like dermatofibroma with mast cells.
- Source :
-
The American Journal of dermatopathology [Am J Dermatopathol] 2011 Aug; Vol. 33 (6), pp. e74-6. - Publication Year :
- 2011
-
Abstract
- We report an unusual case of hemangiopericytoma-like dermatofibroma in the right shoulder of an 82-year-old patient with a well-defined nodular growth located in the dermis. Microscopic study revealed a band of haphazardly arranged cells with a vascular component of gaping, simple, endothelial-lined vascular structures with intervening postcapillary venules and capillary-sized slit-like "staghorn" vascular channels filled with erythrocytes; abundant mast cells were also observed. The neoplasm cells were positive for CD68 and Factor XIIIA and negative for CD34. Few data have been published on the presence of abundant mast cells (tryptase and CD117 positive) in these neoplasm. The differential diagnosis of this entity should consider other spindle cell neoplasm, including hemangiopericytoma/solitary fibrous tumor, dermatofibrosarcoma protuberans, myopericytoma, angioleiomyoma, amelanotic melanoma, pecoma, and benign and malignant peripheral nerve tumors. We present an infrequent case of dermatofibroma with a vascular pattern resembling hemangiopericytoma and the presence of abundant mast cells, which may be responsible for this vascular component.
- Subjects :
- Aged, 80 and over
Angiomyoma diagnosis
Antigens, CD metabolism
Antigens, Differentiation, Myelomonocytic metabolism
Biomarkers, Tumor metabolism
Dermatofibrosarcoma diagnosis
Diagnosis, Differential
Factor XIIIa metabolism
Hemangiopericytoma metabolism
Hemangiopericytoma surgery
Histiocytoma, Benign Fibrous metabolism
Histiocytoma, Benign Fibrous surgery
Humans
Male
Mast Cells metabolism
Melanoma, Amelanotic diagnosis
Peripheral Nervous System Neoplasms diagnosis
Perivascular Epithelioid Cell Neoplasms diagnosis
Skin Neoplasms metabolism
Skin Neoplasms surgery
Solitary Fibrous Tumors diagnosis
Treatment Outcome
Hemangiopericytoma pathology
Histiocytoma, Benign Fibrous pathology
Mast Cells pathology
Skin Neoplasms pathology
Subjects
Details
- Language :
- English
- ISSN :
- 1533-0311
- Volume :
- 33
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- The American Journal of dermatopathology
- Publication Type :
- Academic Journal
- Accession number :
- 21712684
- Full Text :
- https://doi.org/10.1097/DAD.0b013e31821e1a47