Back to Search
Start Over
[The basis of ischemia-reperfusion and myocardial protection].
- Source :
-
Annales francaises d'anesthesie et de reanimation [Ann Fr Anesth Reanim] 2011 May; Vol. 30 Suppl 1, pp. S2-16. - Publication Year :
- 2011
-
Abstract
- The myocardial infarction represents a major cause of mortality. The deleterious phenomena arising during the ischaemia and the reperfusion of the myocardium are studied for more than 40 years. We thought for a long time that the ischaemia was the harmful stage, at the origin of the decrease of the energy stores, the dysregulation of the ionic homeostasis and the metabolic deregulation. We know now that the reperfusion itself is also a source of noxious effects (calcium overload, free radicals production, mitochondrion alteration). To combat these deleterious processes, two maneuvers demonstrated their efficiency by protecting the ischemic myocardium : it is the preconditioning and the postconditionning.<br /> (Copyright © 2011 Elsevier Masson SAS. All rights reserved.)
- Subjects :
- Animals
Arrhythmias, Cardiac etiology
Body Temperature physiology
Collateral Circulation
Humans
Myocardial Reperfusion
Myocardial Reperfusion Injury physiopathology
Myocardial Stunning therapy
Necrosis etiology
Swine
Coronary Circulation physiology
Ischemic Postconditioning methods
Ischemic Preconditioning, Myocardial methods
Myocardial Reperfusion Injury pathology
Myocardial Reperfusion Injury prevention & control
Subjects
Details
- Language :
- French
- ISSN :
- 1769-6623
- Volume :
- 30 Suppl 1
- Database :
- MEDLINE
- Journal :
- Annales francaises d'anesthesie et de reanimation
- Publication Type :
- Academic Journal
- Accession number :
- 21703480
- Full Text :
- https://doi.org/10.1016/S0750-7658(11)70002-8