Practical use of GenoType® HelicoDR, a molecular test for Helicobacter pylori detection and susceptibility testing.

Authors :: Miendje Deyi VY
Burette A
Bentatou Z
Maaroufi Y
Bontems P
Lepage P
Reynders M
Source :: Diagnostic microbiology and infectious disease [Diagn Microbiol Infect Dis] 2011 Aug; Vol. 70 (4), pp. 557-60. Date of Electronic Publication: 2011 Jun 22.
Publication Year :: 2011
Abstract: Compared to culture-based method, the sensitivity, specificity, positive, and negative predictive values of the GenoType(®) HelicoDR for detecting Helicobacter pylori resistance were, respectively, 100, 86.2, 89.7%, and 100% to clarithromycin as well as 82.6, 95.1, 90.5%, and 90.7% to fluoroquinolones. This molecular assay detected a mixture of genotypes and could successfully analyze biopsies without transport/storage limitations.<br /> (Copyright © 2011 Elsevier Inc. All rights reserved.)

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