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Metatypical carcinoma. A review of 327 cases.
- Source :
-
Annali italiani di chirurgia [Ann Ital Chir] 2011 Mar-Apr; Vol. 82 (2), pp. 131-5. - Publication Year :
- 2011
-
Abstract
- Introduction: Metatypical cell carcinoma is a quite rare malignancy (5% of all non melanoma skin cancers), with features of basal cell carcinoma and squamous cell carcinoma. It is described as coexistence of basal cell carcinoma and squamous cell carcinoma with no transition zone between them.<br />Materials and Methods: We performed a retrospective study of 327 consecutive patients, diagnosed for metatypical carcinoma. Statistical analysis was made to determinate most affected areas, gender prevalence, average age, presence of ulceration and infiltration, peripheral clearance rate.<br />Results: A relevant difference came out between two genders. Chi-square test emphasized a relation between females and the presence of carcinoma on the scalp. In addition a strong correlation between mixed subtype and ulceration was evident. A strong relation between intermediate subtype and positive surgical margin was found; this data could identify a more aggressive behavior of intermediate type.<br />Discussion: Differently from melanoma that usually arises on sun exposed areas, no relation was found between sun exposion and this tumor. This characteristic stresses on the importance of other risks factor apart from sun exposition.<br />Conclusions: We identify some correlation between our data that cannot be explained with previous interpretation of sun exposition.
- Subjects :
- Abdomen pathology
Aged
Algorithms
Carcinoma, Basosquamous therapy
Chi-Square Distribution
Face pathology
Female
Humans
Lower Extremity pathology
Male
Neck pathology
Neoplasm, Residual pathology
Retrospective Studies
Risk Factors
Scalp pathology
Sex Factors
Skin Neoplasms therapy
Thorax pathology
Upper Extremity pathology
Carcinoma, Basosquamous pathology
Skin Neoplasms pathology
Subjects
Details
- Language :
- English
- ISSN :
- 0003-469X
- Volume :
- 82
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Annali italiani di chirurgia
- Publication Type :
- Academic Journal
- Accession number :
- 21682103