Post-irradiation "acquired cavernous angiomas" with drug resistant seizures.

Authors :: Menon RN
Baheti NN
Cherian A
Rathore C
Iyer RS
Radhakrishnan A
Source :: Epilepsy research [Epilepsy Res] 2011 Sep; Vol. 96 (1-2), pp. 161-5. Date of Electronic Publication: 2011 Jun 15.
Publication Year :: 2011
Abstract: Cavernomas are well-known congenital vascular lesions with presumably high epileptogenicity. We report two patients who developed cavernomas; both were in remission from childhood acute lymphoblastic leukemia following standard chemo-radiotherapy. They developed drug-resistant focal epilepsy secondary to cavernomas and were subjected to surgical/medical management. This report highlights the ictogenesis of radiation-induced "acquired" cavernous angiomatosis in the brain. Appropriate treatment, including resection of these lesions in selected cases, improves the quality of life in such patients.<br /> (Copyright © 2011 Elsevier B.V. All rights reserved.)