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[Clinical efficacy and safety of CPT-11+CDDP therapy as third-line chemotherapy for advanced and recurrent gastric cancer].
- Source :
-
Gan to kagaku ryoho. Cancer & chemotherapy [Gan To Kagaku Ryoho] 2011 Jun; Vol. 38 (6), pp. 945-9. - Publication Year :
- 2011
-
Abstract
- The clinical efficacy and safety of CPT-11+CDDP therapy were studied retrospectively in 34 patients with advanced and recurrent gastric cancer. The overall response rate was 5. 9%; MST was 209 days. The adverse effects observed were grade 3 in 7 patients(20. 6%). CPT-11+CDDP therapy could be useful and safe as third-line chemotherapy.
- Subjects :
- Adult
Aged
Aged, 80 and over
Antineoplastic Combined Chemotherapy Protocols adverse effects
Camptothecin administration & dosage
Camptothecin adverse effects
Camptothecin therapeutic use
Cisplatin administration & dosage
Cisplatin adverse effects
Female
Humans
Irinotecan
Male
Middle Aged
Neoplasm Staging
Recurrence
Stomach Neoplasms pathology
Survival Rate
Antineoplastic Combined Chemotherapy Protocols therapeutic use
Camptothecin analogs & derivatives
Cisplatin therapeutic use
Salvage Therapy
Stomach Neoplasms drug therapy
Subjects
Details
- Language :
- Japanese
- ISSN :
- 0385-0684
- Volume :
- 38
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- Gan to kagaku ryoho. Cancer & chemotherapy
- Publication Type :
- Academic Journal
- Accession number :
- 21677484