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Molecular epidemiology of strangles outbreaks in the UK during 2010.
- Source :
-
The Veterinary record [Vet Rec] 2011 Jun 25; Vol. 168 (25), pp. 666. Date of Electronic Publication: 2011 Jun 14. - Publication Year :
- 2011
-
Abstract
- The sequence of the Streptococcus equi subspecies equi (S equi) M-like protein (SeM) gene was determined for 105 isolates of S equi from strangles outbreaks in the UK during 2010 and compared with previous data from 2007 to 2008. Twenty-three distinct alleles were identified, including 11 novel alleles. One allele giving rise to a putative truncated M protein was identified from the guttural pouch of an asymptomatic carrier. Allele 9 was the most prevalent, comprising 57.7 per cent of isolates, followed by allele 6 (10.3 per cent). Significant changes in allele prevalence were found between 2007, 2008 and 2010, with an increasing prevalence in SeM-9-related alleles and a corresponding decreasing prevalence in SeM-6-related alleles observed over the period (P<0.001). Geographical proximity of outbreaks caused by some uncommon alleles was apparent between 2007, 2008 and 2010.
- Subjects :
- Alleles
Animals
Bacterial Proteins genetics
Carrier Proteins genetics
Horse Diseases microbiology
Horses
Molecular Epidemiology
Nasopharynx microbiology
Polymerase Chain Reaction veterinary
Sentinel Surveillance veterinary
Streptococcal Infections epidemiology
Streptococcal Infections microbiology
Streptococcus equi genetics
United Kingdom epidemiology
DNA, Bacterial genetics
Disease Outbreaks veterinary
Horse Diseases epidemiology
Streptococcal Infections veterinary
Streptococcus equi isolation & purification
Subjects
Details
- Language :
- English
- ISSN :
- 2042-7670
- Volume :
- 168
- Issue :
- 25
- Database :
- MEDLINE
- Journal :
- The Veterinary record
- Publication Type :
- Academic Journal
- Accession number :
- 21672953
- Full Text :
- https://doi.org/10.1136/vr.d1485