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Morbillivirus infection in pilot whales: strict protein requirement drives genetic conservation.
- Source :
-
Archives of virology [Arch Virol] 2011 Oct; Vol. 156 (10), pp. 1853-9. Date of Electronic Publication: 2011 Jun 14. - Publication Year :
- 2011
-
Abstract
- Morbillivirus infection of marine mammals has been documented across all of the world's oceans. Whilst infection is generally demonstrated using a variety of histopathological and serological techniques, where possible, the use of molecular techniques is being used to enable accurate genetic typing of virus strains through sequence analysis. Here, we present genetic data from dolphins and pilot whales affected by morbillivirus infection in the recent outbreak in the Mediterranean Sea during a six-month period from the end of October 2006 to April 2007. To date, very few studies have looked at characterizing outbreaks of morbillivirus infections in whale species at the molecular level. Here, we provide a full sequence for the haemagglutinin (H) gene from material derived from both a dolphin and a pilot whale from the 2007 outbreak in the Mediterranean Sea and show this virus to be 100% identical across the region analysed. Furthermore, we compare partial sequence data from the nucleocapsid (N) gene of the pilot whale material with previously published data and show evidence for strong protein conservation between these different isolates. Finally, we discuss the current classification of cetacean morbilliviruses as a single species.
- Subjects :
- Amino Acid Sequence
Animals
Base Sequence
Conserved Sequence
Genetic Variation
Lectins chemistry
Lectins genetics
Lectins metabolism
Molecular Sequence Data
Morbillivirus classification
Morbillivirus physiology
Morbillivirus Infections genetics
Morbillivirus Infections virology
Phylogeny
Sequence Alignment
Viral Proteins chemistry
Viral Proteins metabolism
Morbillivirus genetics
Morbillivirus isolation & purification
Morbillivirus Infections veterinary
Viral Proteins genetics
Whales, Pilot virology
Subjects
Details
- Language :
- English
- ISSN :
- 1432-8798
- Volume :
- 156
- Issue :
- 10
- Database :
- MEDLINE
- Journal :
- Archives of virology
- Publication Type :
- Academic Journal
- Accession number :
- 21671040
- Full Text :
- https://doi.org/10.1007/s00705-011-1042-8