[Ismail Pasha and the treatise on cholera (Kolera Risâlesi)].

Since the beginning of 19th century, cholera, which was an endemic disease in India and Bengal, started epidemics in Europe and Middle East and affected the Ottoman Empire first in 1831. Ismail Pasha, who was one of the last Ottoman hekimbashis, wrote a treatise named "Kolera Risalesi" (The Treatise on Cholera), after the cholera epidemic that had broken out in Istanbul in October 1847. In this treatise, which aimed to inform people about cholera, description and causes of cholera is briefly described, and precautions which are necessary to prevent the disease and treatment methods be performed after the disease spread.