[AMD: Future therapies].

Authors :: Cohen SY
Girmens JF
Source :: Journal francais d'ophtalmologie [J Fr Ophtalmol] 2011 Sep; Vol. 34 (7), pp. 498-501. Date of Electronic Publication: 2011 Jun 11.
Publication Year :: 2011
Abstract: Many drugs are presently tested in the different types of age-related macular degeneration (AMD), i.e. geographic atrophy or exudative AMD. In atrophic AMD, drugs attempt to spare the photoreceptors and the retinal pigment epithelium to prevent the oxidative damages or to suppress the inflammation process. In exudative AMD, some drugs try to challenge the available anti-VEGF drugs but others try to improve the visual prognosis in targeting other mechanisms or cells involved in angiogenesis, such as pericytes. The present article aims to summarize the available data, given in scientific meetings or given by the companies.<br /> (Copyright © 2011 Elsevier Masson SAS. All rights reserved.)