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Oxyfold: a simple and efficient solid-supported reagent for disulfide bond formation.

Authors :
VerdiƩ P
Ronga L
Cristau M
Amblard M
Cantel S
Enjalbal C
Puget K
Martinez J
Subra G
Source :
Chemistry, an Asian journal [Chem Asian J] 2011 Sep 05; Vol. 6 (9), pp. 2382-9. Date of Electronic Publication: 2011 Jun 07.
Publication Year :
2011

Abstract

The synthesis and use of novel polymer-supported reagents for disulfide bond formation is described. This family of supported reagents consists of a series of oxidized methionines grafted onto a solid support. Their cost and the simplicity of their preparation through N-carboxyanhydride polymerization on beads make them reactants of choice for the formation of disulfide bridges in peptides.<br /> (Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.)

Details

Language :
English
ISSN :
1861-471X
Volume :
6
Issue :
9
Database :
MEDLINE
Journal :
Chemistry, an Asian journal
Publication Type :
Academic Journal
Accession number :
21656691
Full Text :
https://doi.org/10.1002/asia.201100202