Ghrelin and cancer.

Authors :: Chopin L
Walpole C
Seim I
Cunningham P
Murray R
Whiteside E
Josh P
Herington A
Source :: Molecular and cellular endocrinology [Mol Cell Endocrinol] 2011 Jun 20; Vol. 340 (1), pp. 65-9. Date of Electronic Publication: 2011 May 25.
Publication Year :: 2011
Abstract: Ghrelin is a peptide hormone that was originally isolated from the stomach as the endogenous ligand for the growth hormone secretagogue receptor (GHSR). Ghrelin has many functions, including the regulation of appetite and gut motility, growth hormone release from the anterior pituitary and roles in the cardiovascular and immune systems. Ghrelin and its receptor are expressed in a number of cancers and cancer cell lines and may play a role in processes associated with cancer progression, including cell proliferation, apoptosis, and cell invasion and migration.<br /> (Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.)