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fMRI of the sensorimotor cortex in patients with traumatic brain injury after intensive rehabilitation.
- Source :
-
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology [Neurol Sci] 2011 Aug; Vol. 32 (4), pp. 633-9. Date of Electronic Publication: 2011 May 24. - Publication Year :
- 2011
-
Abstract
- For evaluating the patterns of brain activation in sensorimotor areas following motor rehabilitation, seven male patients diagnosed with TBI underwent an fMRI study before and after being subjected to motor rehabilitation. Six patients showed a reduction in the BOLD signal of their motor cortical areas during the second fMRI evaluation. A decrease in cerebellum activation was also observed in two patients. Newly activated areas, were observed in four patients after treatment. In addition, an increase in the activation of the supplementary motor area (SMA) following rehabilitation was observed in only one test subject. The findings show that motor rehabilitation in TBI patients produces a decrease in the BOLD signal for the sensorimotor areas that were activated prior to treatment. In addition, we observed the recruitment of different brain areas to compensate for functional loss due to TBI in line with the cortical reorganisation mechanism.
- Subjects :
- Adult
Body Weight
Cerebellum physiology
Data Interpretation, Statistical
Gait physiology
Humans
Image Processing, Computer-Assisted
Magnetic Resonance Imaging
Male
Oxygen blood
Physical Education and Training
Recruitment, Neurophysiological
Young Adult
Brain Injuries pathology
Brain Injuries rehabilitation
Motor Cortex pathology
Somatosensory Cortex pathology
Subjects
Details
- Language :
- English
- ISSN :
- 1590-3478
- Volume :
- 32
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
- Publication Type :
- Academic Journal
- Accession number :
- 21607756
- Full Text :
- https://doi.org/10.1007/s10072-011-0604-6