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Enantioselective synthesis of diverse sulfinamides and sulfinylferrocenes from phenylglycine-derived chiral sulfinyl transfer agent.
- Source :
-
The Journal of organic chemistry [J Org Chem] 2011 Jul 01; Vol. 76 (13), pp. 5480-4. Date of Electronic Publication: 2011 Jun 07. - Publication Year :
- 2011
-
Abstract
- A new chiral sulfinyl transfer auxiliary derived from readily available phenylglycine was developed. This auxiliary is utilized to synthesize a diverse array of alkyl- and arylsulfinamides and sulfinylferrocenes in high yields and excellent ee's. The desired products are produced in a one-pot sequence from the oxathiazolidine 2-oxide by two sequential nucleophilic additions that proceed in a stereospecific manner.
Details
- Language :
- English
- ISSN :
- 1520-6904
- Volume :
- 76
- Issue :
- 13
- Database :
- MEDLINE
- Journal :
- The Journal of organic chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 21598997
- Full Text :
- https://doi.org/10.1021/jo200715c