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[Preclinical evaluation of the effect of Metrop GP on acute toxicity and hepatotoxicity of chemotherapy].
- Source :
-
Voprosy onkologii [Vopr Onkol] 2011; Vol. 57 (1), pp. 71-4. - Publication Year :
- 2011
-
Abstract
- Our paper presents the results of preclinical evaluation of the mitigating effect of Metrop GP on the acute toxicity and hepatotoxicity induced by paclitaxel and doxorubicin treatment using functional samples and biochemical and morphological techniques.
- Subjects :
- Animals
Antineoplastic Combined Chemotherapy Protocols administration & dosage
Antioxidants administration & dosage
Biomarkers blood
Cell Membrane drug effects
Doxorubicin administration & dosage
Drug Administration Schedule
Female
Liver pathology
Male
Organ Size
Paclitaxel administration & dosage
Rats
Time Factors
Antineoplastic Combined Chemotherapy Protocols adverse effects
Antioxidants pharmacology
Honey
Liver drug effects
Liver metabolism
Subjects
Details
- Language :
- Russian
- ISSN :
- 0507-3758
- Volume :
- 57
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Voprosy onkologii
- Publication Type :
- Academic Journal
- Accession number :
- 21598712