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Fetopathological investigations after induced abortions performed in mid-term gemini pregnancies.

Authors :
Joó GJ
Csatlós E
Börzsönyi B
Demendi C
Rigó J Jr
Source :
Pathology, research and practice [Pathol Res Pract] 2011 Jul 15; Vol. 207 (7), pp. 443-7. Date of Electronic Publication: 2011 May 19.
Publication Year :
2011

Abstract

Multiple pregnancies present a special obstetric condition whose importance has increased due to the spread of assisted reproductive techniques. We have processed the fetopathological data of 43 abortions induced in mid-term gemini pregnancies, owing to malformations affecting one or both fetuses. 67.4% of the gemini pregnancies were conceived naturally and 32.6% by assisted reproduction techniques. The most commonly occurring malformations affected the fetuses' cardiovascular and central nervous systems. Positive histories could be detected in 23% of the cases. The male-to-female ratio was found to be 1.14. In the majority of the cases with central nervous system malformation, fetus "A" was affected (85.7%). In 29.4% of the cases, monochorionic placentation was established. Ultrasonography and fetopatological findings yielded perfectly matching results in 78.9% of the cases. The incidence of fetal malformations is probably not higher among fetuses conceived by assisted reproduction techniques compared to the ones conceived naturally. Fetal central nervous system malformations usually affect fetus "A". Based on the results of the fetopathological examinations, ultrasonography is a reliable method in the diagnostics of malformations affecting twin fetuses. Fetal echocardiography is indicated simply because of the pregnancy being a multiple one.<br /> (Copyright © 2011 Elsevier GmbH. All rights reserved.)

Details

Language :
English
ISSN :
1618-0631
Volume :
207
Issue :
7
Database :
MEDLINE
Journal :
Pathology, research and practice
Publication Type :
Academic Journal
Accession number :
21596482
Full Text :
https://doi.org/10.1016/j.prp.2011.04.003