1-Bromo-2-(10β-dihydro-artemisin-oxy)ethane.

Authors :: Lombard MC
Fernandes MA
Breytenbach JC
N'da DD
Source :: Acta crystallographica. Section E, Structure reports online [Acta Crystallogr Sect E Struct Rep Online] 2010 Jul 31; Vol. 66 (Pt 8), pp. o2182-3. Date of Electronic Publication: 2010 Jul 31.
Publication Year :: 2010
Abstract: The title compound, C(17)H(27)BrO(5), DEB, is a derivative of artemisinin which is used in malara therapy. The OR-group at C12 is cis to the CH(3)-group at C11 and axially oriented on ring D which has a chair conformation. The crystal packing is stabilized by several weak inter-molecular C-H⋯O inter-actions, which combine to form a C-H-O bonded network parallel to (001).