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5-Chloro-N-[2-(1H-imidazol-4-yl)eth-yl]-N-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine.
- Source :
-
Acta crystallographica. Section E, Structure reports online [Acta Crystallogr Sect E Struct Rep Online] 2009 Dec 24; Vol. 66 (Pt 1), pp. o242. Date of Electronic Publication: 2009 Dec 24. - Publication Year :
- 2009
-
Abstract
- The title compound, C(12)H(13)ClN(6), was prepared by reaction of 4,5-dichloro-7H-pyrrolo[2,3-d]pyrimidine with 2-(1H-imid-azol-4-yl)-N-methyl-ethanamine, and the X-ray study confirmed that chloro-substituent in six-membered ring was replaced in the reaction. The exocyclic N atom environment is approximately coplanar with the pyrrolo[2,3-d]pyrimidine [corresponding dihedral angle is 5.5 (1)°], whereas the mean plane of the N-C-C-C link connecting with the imidazolyl ring is almost exactly orthogonal to the plane of the bicyclic system [dihedral angle = 91.6 (2)°]. The imidazolyl plane itself, however, forms a relatively small dihedral angle of 20.8 (1)° with the pyrrolo[2,3-d]pyrimidine plane. There are two independent N-H⋯N hydrogen bonds in the structure, which link mol-ecules into layers parallel to (03).
Details
- Language :
- English
- ISSN :
- 1600-5368
- Volume :
- 66
- Issue :
- Pt 1
- Database :
- MEDLINE
- Journal :
- Acta crystallographica. Section E, Structure reports online
- Publication Type :
- Academic Journal
- Accession number :
- 21580123
- Full Text :
- https://doi.org/10.1107/S1600536809054750