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Chronic recurrent vaginal candidosis: easy to treat, difficult to cure. Results of intermittent treatment with a new oral antifungant.
- Source :
-
European journal of obstetrics, gynecology, and reproductive biology [Eur J Obstet Gynecol Reprod Biol] 1990 Apr; Vol. 35 (1), pp. 75-83. - Publication Year :
- 1990
-
Abstract
- Research into the pathogenesis and treatment of chronic recurrent candidosis vaginalis did not come up with a clear answer of curing this phenomenon. In this investigation, data are presented of a therapy with a new antifungal agent, itraconazole. After a therapeutic treatment course, 17 patients received a prophylaxis for CRCV over 6 months. The treatment schedule for prophylaxis consisted of 4 capsules of 50 mg itraconazole on day 5 and 6 of the menstrual cycle. Eleven remained symptom-free in this period. Although there is no explanation for recurrence in most cases of CRCV, intermittent treatment schedules can be used to treat but not to cure these patients. Data of this investigation and data mentioned in the literature prove the necessity to discriminate between a sympatomtic and a mycological cure.
- Subjects :
- Administration, Oral
Adult
Antifungal Agents administration & dosage
Chronic Disease
Drug Administration Schedule
Female
Humans
Itraconazole
Ketoconazole administration & dosage
Ketoconazole therapeutic use
Menstrual Cycle
Middle Aged
Recurrence
Antifungal Agents therapeutic use
Candidiasis, Vulvovaginal drug therapy
Ketoconazole analogs & derivatives
Subjects
Details
- Language :
- English
- ISSN :
- 0301-2115
- Volume :
- 35
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- European journal of obstetrics, gynecology, and reproductive biology
- Publication Type :
- Academic Journal
- Accession number :
- 2155833
- Full Text :
- https://doi.org/10.1016/0028-2243(90)90145-q