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The sensitivity of Neisseria gonorrhoeae, Chlamydia trachomatis, and herpes simplex type II to disinfection with povidone-iodine.
- Source :
-
American journal of ophthalmology [Am J Ophthalmol] 1990 Mar 15; Vol. 109 (3), pp. 329-33. - Publication Year :
- 1990
-
Abstract
- Povidone-iodine is an effective broad-spectrum disinfectant with no reported toxicity to the cornea and conjunctiva when applied topically in single dose to the ocular surface. We challenged four strains of Neisseria gonorrhoeae, a clinical isolate of Chlamydia trachomatis, and one strain of herpes simplex virus type II with three different concentrations of povidone-iodine (5%, 1%, and 0.1%) for one minute. The challenge inoculum of Neisseria gonorrhoeae and herpes simplex virus type II were completely sterilized by all three solutions. The chlamydia titer was reduced by two log units at the 5% and 1% concentrations, but not the 0.1% concentration. Povidone-iodine may be of potential use in the prophylaxis of newborns against ophthalmia neonatorum.
- Subjects :
- Blood microbiology
Cervix Uteri microbiology
Conjunctiva microbiology
Female
Humans
Infant, Newborn
Neisseria gonorrhoeae isolation & purification
Ophthalmia Neonatorum prevention & control
Povidone
Povidone-Iodine therapeutic use
Chlamydia trachomatis drug effects
Neisseria gonorrhoeae drug effects
Povidone-Iodine pharmacology
Simplexvirus drug effects
Subjects
Details
- Language :
- English
- ISSN :
- 0002-9394
- Volume :
- 109
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- American journal of ophthalmology
- Publication Type :
- Academic Journal
- Accession number :
- 2155533
- Full Text :
- https://doi.org/10.1016/s0002-9394(14)74560-x