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Clinical trials in recurrent ovarian cancer.
- Source :
-
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society [Int J Gynecol Cancer] 2011 May; Vol. 21 (4), pp. 771-5. - Publication Year :
- 2011
-
Abstract
- The 4th Ovarian Cancer Consensus Conference of the Gynecologic Cancer InterGroup was held in Vancouver, Canada, in June 2010. Representatives of 23 cooperative research groups studying gynecologic cancers gathered to establish international consensus on issues critical to the conduct of large randomized trials. Group C, 1 of the 3 discussion groups, examined recurrent ovarian cancer, and we report the consensus reached regarding 4 questions. These included the following: (1) What is the role of cytoreductive surgery for recurrent ovarian cancer? (2) How do we define distinct patient populations in need of specific therapeutic approaches? (3) Should end points for trials with recurrent disease vary from those of first-line trials? (4) Is CA-125 progression alone sufficient for entry/eligibility into clinical trials?
- Subjects :
- Carcinoma pathology
Clinical Trials as Topic trends
Consensus
Endpoint Determination methods
Female
Gynecologic Surgical Procedures methods
Gynecologic Surgical Procedures trends
Humans
Neoadjuvant Therapy
Ovarian Neoplasms pathology
Recurrence
Carcinoma therapy
Clinical Trials as Topic methods
Ovarian Neoplasms therapy
Subjects
Details
- Language :
- English
- ISSN :
- 1525-1438
- Volume :
- 21
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- International journal of gynecological cancer : official journal of the International Gynecological Cancer Society
- Publication Type :
- Academic Journal
- Accession number :
- 21543939
- Full Text :
- https://doi.org/10.1097/IGC.0b013e31821bb8aa