Circulating osteogenic cells: implications for injury, repair, and regeneration.

Authors :: Pignolo RJ
Kassem M
Source :: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research [J Bone Miner Res] 2011 Aug; Vol. 26 (8), pp. 1685-93. Date of Electronic Publication: 2011 May 02.
Publication Year :: 2011
Abstract: The aim of this review is to provide a critical reading of recent literature pertaining to the presence of circulating, fluid-phase osteoblastic cells and their possible contribution to bone formation. We have termed this group of cells collectively as circulating osteogenic precursor (COP) cells. We present evidence for their existence, methods used for their isolation and identification, possible physiological and pathophysiological roles, cellular origins, and possible mechanisms for their migration to target tissues.<br /> (Copyright © 2011 American Society for Bone and Mineral Research.)

Subjects :: Animals
Humans
Stem Cells cytology
Cell Movement
Osteoblasts pathology
Osteogenesis
Regeneration
Wound Healing

Language :: English
ISSN :: 1523-4681
Volume :: 26
Issue :: 8
Database :: MEDLINE
Journal :: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Publication Type :: Academic Journal
Accession number :: 21538513
Full Text :: https://doi.org/10.1002/jbmr.370

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