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1-[2-(4-Nitro-phen-yl)-5-(5-phenyl-1,2-oxazol-3-yl)-1,2,3,4-tetra-hydro-quinolin-4-yl]pyrrolidin-2-one monohydrate.

Authors :
Gutierrez M
Vallejos G
Fernández C
Cárdenas A
Brito I
Source :
Acta crystallographica. Section E, Structure reports online [Acta Crystallogr Sect E Struct Rep Online] 2010 Dec 18; Vol. 67 (Pt 1), pp. o175-6. Date of Electronic Publication: 2010 Dec 18.
Publication Year :
2010

Abstract

The title compound, C(28)H(24)N(4)O(4)·H(2)O, crystallizes with two organic mol-ecules and two solvent water mol-ecules in the asymmetric unit. The most obvious difference between the mol-ecules is the torsion angles between the isoxazole ring and the benzene and phenyl rings [47.0 (2)/56.4 (2) and 33.3 (2)/11.0 (2)°, respectively]. Another important difference is observed in the rotation of the nitro group with respect to the phenyl groups [3.5 (6) and 31.1 (6)°]. The pyrrolidinone fragment is cis oriented with respect to the 4-nitro-phenyl fragment. In the crystal, mol-ecules are linked into centrosymmetric R(4) (2)(8) and R(4) (4)(20) motifs by O-H⋯O and N-H⋯O inter-actions.

Details

Language :
English
ISSN :
1600-5368
Volume :
67
Issue :
Pt 1
Database :
MEDLINE
Journal :
Acta crystallographica. Section E, Structure reports online
Publication Type :
Academic Journal
Accession number :
21522681
Full Text :
https://doi.org/10.1107/S1600536810052463