Back to Search Start Over

N-cyanomethylnorboldine: a new aporphine isolated from Alseodaphne perakensis (Lauraceae).

Authors :
Nafiah MA
Mukhtar MR
Omar H
Ahmad K
Morita H
Litaudon M
Awang K
Hadi AH
Source :
Molecules (Basel, Switzerland) [Molecules] 2011 Apr 20; Vol. 16 (4), pp. 3402-9. Date of Electronic Publication: 2011 Apr 20.
Publication Year :
2011

Abstract

A phytochemical study of the bark of Alseodaphne perakensis has yielded three aporphine alkaloids: the new compound N-cyanomethylnorboldine (1), and the two known alkaloids N-methyllaurotetanine (2) and norboldine (3). The isolation was achieved by chromatographic techniques and the structural elucidation was performed via spectral methods, notably 1D- and 2D-NMR, UV, IR, and HRFABMS. The vasorelaxation activity of compound 1 has been studied.

Details

Language :
English
ISSN :
1420-3049
Volume :
16
Issue :
4
Database :
MEDLINE
Journal :
Molecules (Basel, Switzerland)
Publication Type :
Academic Journal
Accession number :
21512448
Full Text :
https://doi.org/10.3390/molecules16043402