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Inhibition of cysteine peptidase activity in ascitic fluid in pancreatic cancer patients.

Authors :
Agrawal AK
Kielan W
Katib A
Grzebieniak Z
Skalski A
Grzebieniak T
Duda-Barcik L
Janocha A
Siewiński M
Source :
Folia histochemica et cytobiologica [Folia Histochem Cytobiol] 2010 Dec; Vol. 48 (4), pp. 513-7.
Publication Year :
2010

Abstract

The work's objective is to answer the question whether there is any possibility of activity inhibition of cysteine peptidases inhibitors playing an important role in key processes accompanying cancer formation, including pancreas. There is a justified speculation that specific inhibitors of these enzymes may inhibit development of cancer processes by inhibiting their activity. In vitro studies confirmed that these enzymes in ascitic fluid were inhibited with egg whites inhibitors even to 90% of their original activity.

Details

Language :
English
ISSN :
1897-5631
Volume :
48
Issue :
4
Database :
MEDLINE
Journal :
Folia histochemica et cytobiologica
Publication Type :
Academic Journal
Accession number :
21478091
Full Text :
https://doi.org/10.2478/v10042-010-0057-4