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Carcinosarcoma ex eccrine spiradenoma of the vulva: report of the first case.
- Source :
-
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists [Int J Gynecol Pathol] 2011 May; Vol. 30 (3), pp. 301-5. - Publication Year :
- 2011
-
Abstract
- Carcinosarcoma is exceedingly rare in the vulva. We describe a case of carcinosarcoma in a 67-year-old female patient who presented with recent enlargement and pain of a vulval nodule noted for 15 years. The excised tumor showed intermixed carcinomatous (adenocarcinoma and anaplastic carcinoma) and sarcomatous elements (osteosarcoma, chondrosarcoma, and leiomyosarcoma), which focally merged with several lobules of typical eccrine spiradenoma. The inguinal lymph nodes showed metastasis of the carcinomatous component only. This case represents the first reported case of vulval carcinosarcoma of the skin adnexal origin, and has to be distinguished from sarcomatoid carcinoma of epidermal origin because of a probable more aggressive behavior.
- Subjects :
- Adenoma, Sweat Gland radiotherapy
Adenoma, Sweat Gland surgery
Aged
Carcinosarcoma radiotherapy
Carcinosarcoma surgery
Cell Transformation, Neoplastic pathology
Eccrine Glands pathology
Female
Humans
Immunohistochemistry
Lymphatic Metastasis pathology
Sweat Gland Neoplasms radiotherapy
Sweat Gland Neoplasms surgery
Vulvar Neoplasms radiotherapy
Vulvar Neoplasms surgery
Adenoma, Sweat Gland pathology
Carcinosarcoma pathology
Sweat Gland Neoplasms pathology
Vulvar Neoplasms pathology
Subjects
Details
- Language :
- English
- ISSN :
- 1538-7151
- Volume :
- 30
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists
- Publication Type :
- Academic Journal
- Accession number :
- 21464722
- Full Text :
- https://doi.org/10.1097/PGP.0b013e3182055a3d