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[The judgement of collagen metabolism by hydroxyproline in plasma and urine and plasma collagenic peptidase under different diet (author's transl)].

Authors :
Regnitter W
Smidt U
Worth G
Source :
Klinische Wochenschrift [Klin Wochenschr] 1978 Oct 15; Vol. 56 (20), pp. 1001-5.
Publication Year :
1978

Abstract

In 34 subjects--coal workers with pneumoconiosis, patients with collagenic diseases and healthy subjects--the daily urinary excretion of hydroxyproline (HP) and the plasma concentrations of HP and of collagenic peptidase have been measured during one week under HP-free and HP-enriched diet. It is shown that a 24-hour period of HP-free diet is necessary and sufficient before collecting urine or plasma for diet independent measurements of total or non-protein bound HP. Concentrations in plasma correlate well with the amounts excreted in urine. Collagenic peptidase is independent from the diet and well suited for assessment of the activity of the metabolism of collagene. There are no differences between healthy subjects and coal workers with pneumoconiosis.

Details

Language :
German
ISSN :
0023-2173
Volume :
56
Issue :
20
Database :
MEDLINE
Journal :
Klinische Wochenschrift
Publication Type :
Academic Journal
Accession number :
214624
Full Text :
https://doi.org/10.1007/BF01476664