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Natural product biosynthesis inspired concise and stereoselective synthesis of benzopyrones and related scaffolds.

Authors :
Baskar B
Dakas PY
Kumar K
Source :
Organic letters [Org Lett] 2011 Apr 15; Vol. 13 (8), pp. 1988-91. Date of Electronic Publication: 2011 Mar 18.
Publication Year :
2011

Abstract

A natural product biosynthesis-inspired strategy to explore biologically relevant chemical space is presented. A phosphine-catalyzed cascade and stereoselective annulation provides a common tricyclic benzopyrone intermediate that was efficiently transformed into diverse and related naturally occurring scaffolds.<br /> (© 2011 American Chemical Society)

Details

Language :
English
ISSN :
1523-7052
Volume :
13
Issue :
8
Database :
MEDLINE
Journal :
Organic letters
Publication Type :
Academic Journal
Accession number :
21417315
Full Text :
https://doi.org/10.1021/ol200389p