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[5-FU/l-LV therapy is useful for hemodialysis patients with advanced gastric cancer].
- Source :
-
Gan to kagaku ryoho. Cancer & chemotherapy [Gan To Kagaku Ryoho] 2011 Mar; Vol. 38 (3), pp. 449-51. - Publication Year :
- 2011
-
Abstract
- A 71-year-old man receiving maintenance dialysis because of diabetic nephropathy presented with hematemesis at another hospital in January 2008. A gastrointestinal endoscopy demonstrated a II a-like lesion in the angle of the stomach, and he was admitted to our hospital. A diagnosis of gastric adenocarcinoma (cT2N2M0, Stage IIIA) was made. An operation could not be performed because of the high risk, so combination chemotherapy with 5-FU and l-LV was initiated. After 3 courses of treatment, the size of the primary tumor was markedly reduced. After 6 courses, the primary lesion had changed to a scar, and an endoscopic biopsy revealed no cancer cells. His performance status did not deteriorate, and no serious adverse events occurred during the course of treatment. Chemotherapy was continued because the overall response was SD. 5-FU/l-LV therapy should be considered as a safe and useful treatment for a hemodialysis patient with advanced gastric cancer.
- Subjects :
- Aged
Biopsy
Fluorouracil administration & dosage
Humans
Kidney Failure, Chronic complications
Kidney Failure, Chronic therapy
Leucovorin administration & dosage
Male
Neoplasm Staging
Renal Dialysis
Stomach Neoplasms complications
Stomach Neoplasms pathology
Fluorouracil therapeutic use
Leucovorin therapeutic use
Stomach Neoplasms drug therapy
Subjects
Details
- Language :
- Japanese
- ISSN :
- 0385-0684
- Volume :
- 38
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Gan to kagaku ryoho. Cancer & chemotherapy
- Publication Type :
- Academic Journal
- Accession number :
- 21403452