[Serial FDG-PET evaluation of a patchy pattern of hematopoiesis at diagnosis in aplastic anemia].

Authors :: Hirata H
Arai Y
Inano S
Yoshinaga N
Maruyama W
Fukunaga A
Arima N
Source :: [Rinsho ketsueki] The Japanese journal of clinical hematology [Rinsho Ketsueki] 2011 Feb; Vol. 52 (2), pp. 84-6.
Publication Year :: 2011
Abstract: We investigated the hematopoietic status of aplastic anemia with FDG-PET before and after immunosuppressive therapy. FDG-PET showed a patchy uptake pattern before treatment, indicating residual compensatory hypercellular marrow. Three years after successful treatment with ATG plus CsA, the heterogeneity of bone marrow uptake persisted, suggesting that expanded reconstitution of hematopoiesis may require a long time even after the achievement of hematological remission.

Subjects :: Anemia, Aplastic drug therapy
Autoantibodies administration & dosage
Cyclosporine administration & dosage
Humans
Immunosuppressive Agents administration & dosage
Male
Middle Aged
Anemia, Aplastic diagnostic imaging
Anemia, Aplastic physiopathology
Fluorodeoxyglucose F18
Hematopoiesis
Positron-Emission Tomography
Radiopharmaceuticals

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