Imaging, radiation oncology and randomised trials: time for a change?

We discuss the relevance of current trends in clinical trial conduct in light of the burgeoning need to underpin our practice with evidence, the contribution of novel imaging approaches to provide acceptable surrogate endpoints of effect and their place in the individualised medicine of the future.
(© 2011 The Authors. Journal of Medical Imaging and Radiation Oncology © 2011 The Royal Australian and New Zealand College of Radiologists.)