Back to Search
Start Over
Recognizing and remodeling the nucleosome.
- Source :
-
Current opinion in structural biology [Curr Opin Struct Biol] 2011 Jun; Vol. 21 (3), pp. 335-41. Date of Electronic Publication: 2011 Mar 04. - Publication Year :
- 2011
-
Abstract
- The X-ray structure of the nucleosome core particle (NCP) has been a major milestone in the structural biology of chromatin. Since, our understanding how NCPs interact with multiple partners has been extending from single chromatin-binding domains recognizing post-translational modifications (PTMs) in histone tails towards the recognition of higher-order chromatin structure by multi-subunit chromatin remodeling complexes. The current review summarizes recent progress in the structural biology of nucleosome-recognition from chromatin-binding domains to multi-protein remodeling complexes.<br /> (Copyright © 2011 Elsevier Ltd. All rights reserved.)
- Subjects :
- Adenosine Triphosphate metabolism
Animals
DNA chemistry
DNA metabolism
DNA-Binding Proteins chemistry
DNA-Binding Proteins metabolism
Humans
Ligands
Models, Molecular
Nucleoproteins chemistry
Nucleoproteins metabolism
Protein Binding physiology
Chromatin Assembly and Disassembly
Nucleosomes chemistry
Nucleosomes genetics
Nucleosomes metabolism
Subjects
Details
- Language :
- English
- ISSN :
- 1879-033X
- Volume :
- 21
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Current opinion in structural biology
- Publication Type :
- Academic Journal
- Accession number :
- 21377352
- Full Text :
- https://doi.org/10.1016/j.sbi.2011.02.003