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Frozen-thawed blastocyst transfer reduces ectopic pregnancy risk: an analysis of single embryo transfer cycles in Japan.
- Source :
-
Fertility and sterility [Fertil Steril] 2011 May; Vol. 95 (6), pp. 1966-9. Date of Electronic Publication: 2011 Mar 05. - Publication Year :
- 2011
-
Abstract
- Objective: To evaluate the effect of frozen-thawed blastocyst transfer on ectopic pregnancy (EP) rate.<br />Design: Retrospective analysis.<br />Setting: Japanese registry of assisted reproductive medicine.<br />Patient(s): Women who were registered during 2008.<br />Intervention(s): None.<br />Main Outcome Measure(s): Rates of live birth, EP, and spontaneous abortion in single blastocyst and cleavage-stage ET cycles in both fresh and frozen-thawed were determined.<br />Result(s): In the frozen-thawed single blastocyst transfer cycles, 84 EPs of 10,312 clinical pregnancies (0.81%) were reported. There were 25 EPs of 1,361 clinical pregnancies (1.8%) in fresh IVF single blastocyst transfer cycles and 19 of 1,352 (1.4%) in fresh intracytoplasmic sperm injection single blastocyst transfer cycles. The rate of EPs after frozen-thawed single blastocyst transfers varied between 0.56% and 0.97% after stratification by age group.<br />Conclusion(s): Frozen-thawed blastocyst transfers have reduced EP rates significantly compared with fresh blastocyst transfers.<br /> (Copyright © 2011 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.)
- Subjects :
- Adult
Algorithms
Down-Regulation
Female
Fertilization in Vitro methods
Fertilization in Vitro statistics & numerical data
Freezing
Humans
Japan epidemiology
Menstrual Cycle physiology
Pregnancy
Pregnancy, Ectopic epidemiology
Registries
Retrospective Studies
Risk Factors
Single Embryo Transfer methods
Single Embryo Transfer statistics & numerical data
Embryo Transfer methods
Embryo Transfer statistics & numerical data
Pregnancy, Ectopic etiology
Subjects
Details
- Language :
- English
- ISSN :
- 1556-5653
- Volume :
- 95
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- Fertility and sterility
- Publication Type :
- Academic Journal
- Accession number :
- 21377154
- Full Text :
- https://doi.org/10.1016/j.fertnstert.2011.02.015