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Cardiac magnetic resonance visualizes acute and chronic myocardial injuries in myocarditis.
- Source :
-
The international journal of cardiovascular imaging [Int J Cardiovasc Imaging] 2012 Feb; Vol. 28 (2), pp. 327-35. Date of Electronic Publication: 2011 Feb 24. - Publication Year :
- 2012
-
Abstract
- Our objective was to evaluate the ability of CMR to visualize myocardial injuries over the course of myocarditis. We studied 42 patients (39 males, 3 females; age 37 ± 14 years) with myocarditis during the acute phase and after 12 ± 9 months. CMR included function analyses, T2-weighted imaging (T2 ratio), T1-weighted imaging before and after i.v. gadolinium injection (global relative enhancement; gRE), and late gadolinium enhancement (LGE). In the acute phase, the T2 ratio was elevated in 57%, gRE in 31%, and LGE was present in 64% of the patients. In 32 patients (76%) were any two (or more) out of three sequences abnormal. At follow-up, there was an increase in ejection fraction (57.4 ± 11.9% vs. 61.4 ± 7.6; P < 0.05) while both T2 ratio (2.04 ± 0.32 vs. 1.70 ± 0.28; P < 0.001) and gRE (4.07 ± 1.63 vs. 3.11 ± 1.22; P < 0.05) significantly decreased. The LGE persisted in 10 patients. Dilated cardiomyopathy was present in 3 patients and 4 patients received a defibrillator or a pacemaker. A comprehensive CMR approach is a useful tool to visualize myocardial tissue injuries over the course of myocarditis. CMR may help to differentiate acute from healed myocarditis, and add information for the differential diagnoses.
- Subjects :
- Adult
Chi-Square Distribution
Contrast Media
Diagnosis, Differential
Female
Gadolinium DTPA
Humans
Male
Middle Aged
Myocarditis complications
Myocarditis pathology
Myocarditis physiopathology
Norway
Predictive Value of Tests
Prognosis
Prospective Studies
Retrospective Studies
Stroke Volume
Time Factors
Ventricular Function, Left
Young Adult
Magnetic Resonance Imaging
Myocarditis diagnosis
Myocardium pathology
Subjects
Details
- Language :
- English
- ISSN :
- 1875-8312
- Volume :
- 28
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- The international journal of cardiovascular imaging
- Publication Type :
- Academic Journal
- Accession number :
- 21347598
- Full Text :
- https://doi.org/10.1007/s10554-011-9812-7