Psoriasis induced by cetuximab: a paradoxical adverse effect.

Authors :: Mas-Vidal A
Coto-Segura P
Galache-Osuna C
Santos-Juanes J
Source :: The Australasian journal of dermatology [Australas J Dermatol] 2011 Feb; Vol. 52 (1), pp. 56-8. Date of Electronic Publication: 2010 Aug 16.
Publication Year :: 2011
Abstract: Cetuximab, an epidermal growth factor receptor inhibitor, is a chemotherapeutical agent featuring well-known adverse dermatological effects related to tumour-response prognosis. In psoriasis, the epidermal growth factor receptor is overexpressed; hence, the expectation would be that an epidermal growth factor receptor inhibitor could improve psoriatic lesions. We report a case of psoriasis induced by cetuximab, which was a surprising adverse effect.<br /> (© 2010 The Authors. Australasian Journal of Dermatology © 2010 The Australasian College of Dermatologists.)