Back to Search
Start Over
Acquired opercular epilepsy with oromotor dysfunction: magnetoencephalographic analysis and efficacy of corticosteroid therapy.
- Source :
-
Journal of child neurology [J Child Neurol] 2011 Jul; Vol. 26 (7), pp. 885-90. Date of Electronic Publication: 2011 Feb 15. - Publication Year :
- 2011
-
Abstract
- The authors describe herein the magnetoencephalographic findings and long-term outcome of a girl with acquired opercular epilepsy with oromotor dysfunction. She presented with brief episodes of unconsciousness, tremulous movements of the upper limbs, and negative myoclonus, in addition to convulsive seizures. She also had prolonged episodes of dysarthria and oral motor dysfunction, a gradual decrease in speech output, impairment of finger movements, and deterioration in cognitive performance over several years. Her electroencephalography (EEG) recordings showed notable continuous sharp or sharp-slow discharges during sleep. Brain magnetic resonance images revealed no structural anomalies. Magnetoencephalographic analysis showed broadly distributed epileptic foci around the sylvian fissure, including a secondary source, explaining the specific prolonged neurological dysfunction. Antiepileptic drugs could control her seizures; however, they did not improve the other neurological symptoms or epileptiform discharge on EEG. Administration of low-dose prednisolone over a long period was effective for improving the neurological impairments of this patient.
- Subjects :
- Child
Dysarthria drug therapy
Epilepsy drug therapy
Female
Humans
Landau-Kleffner Syndrome drug therapy
Magnetoencephalography methods
Movement Disorders drug therapy
Treatment Outcome
Adrenal Cortex Hormones therapeutic use
Dysarthria physiopathology
Epilepsy physiopathology
Landau-Kleffner Syndrome physiopathology
Motor Cortex physiopathology
Movement Disorders physiopathology
Subjects
Details
- Language :
- English
- ISSN :
- 1708-8283
- Volume :
- 26
- Issue :
- 7
- Database :
- MEDLINE
- Journal :
- Journal of child neurology
- Publication Type :
- Academic Journal
- Accession number :
- 21325126
- Full Text :
- https://doi.org/10.1177/0883073810393307