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CT of the hips in the investigation of protrusio acetabuli in Marfan syndrome. A case control study.
- Source :
-
European radiology [Eur Radiol] 2011 Jul; Vol. 21 (7), pp. 1485-91. Date of Electronic Publication: 2011 Feb 14. - Publication Year :
- 2011
-
Abstract
- Objectives: To establish the prevalence of protrusio acetabuli (PA) in adults fulfilling the Ghent criteria for Marfan syndrome (MFS), and in a normal adult population.<br />Methods: 105 adults with probable MFS and 107 controls were included. CT of the hips was obtained. A qualitative assessment of PA was performed. A new method for estimating the degree of PA was introduced with measurement of the parameter CWD (circle-wall distance). Results were compared to an alternative method based on MRI [1].<br />Results: 87 of the study group fulfilled the Ghent criteria of MFS (Ghent positives), and 18 did not (Ghent negatives). PA was diagnosed qualitatively in 74.7% of Ghent positive persons, in 27.8% of Ghent negative persons, and in 3.7% of the controls. CWD was significantly different between the three groups (pā<ā0.001). A slight but significant gender difference was found in Ghent positive persons only. The alternative method did not differentiate between the groups with respect to PA, but showed a significant difference between genders.<br />Conclusions: PA was found significantly more often in MFS persons than in controls. Our method was found to be robust and highly reproducible, giving a direct measurement of pelvic protrusion irrespective of pelvic shape.
- Subjects :
- Adult
Aged
Analysis of Variance
Case-Control Studies
Chi-Square Distribution
Female
Humans
Male
Middle Aged
ROC Curve
Acetabulum abnormalities
Acetabulum diagnostic imaging
Marfan Syndrome diagnostic imaging
Marfan Syndrome physiopathology
Musculoskeletal Abnormalities diagnostic imaging
Tomography, X-Ray Computed methods
Subjects
Details
- Language :
- English
- ISSN :
- 1432-1084
- Volume :
- 21
- Issue :
- 7
- Database :
- MEDLINE
- Journal :
- European radiology
- Publication Type :
- Academic Journal
- Accession number :
- 21318473
- Full Text :
- https://doi.org/10.1007/s00330-011-2073-y