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Multiplex cancer cell detection by SERS nanotags with cyanine and triphenylmethine Raman reporters.
- Source :
-
Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2011 Mar 28; Vol. 47 (12), pp. 3514-6. Date of Electronic Publication: 2011 Feb 09. - Publication Year :
- 2011
-
Abstract
- SERS nanotags have been prepared to accomplish the multiplex detection of cancer cells. Herein we evaluated the adequacy of lipoic acid-containing cyanine derivatives (Cy3LA and Cy5LA) to function as multiplex partners with a triphenylmethine Raman reporter (B2LA) under a single excitation wavelength. SERS experiments enabled the multiplex recognition of two different cancer cells with antibody-conjugated nanotags that were derivatized with optimized cyanine and triphenylmethine reporters.
Details
- Language :
- English
- ISSN :
- 1364-548X
- Volume :
- 47
- Issue :
- 12
- Database :
- MEDLINE
- Journal :
- Chemical communications (Cambridge, England)
- Publication Type :
- Academic Journal
- Accession number :
- 21308123
- Full Text :
- https://doi.org/10.1039/c0cc05265e