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Characterization of rabies virus from a human case in Nepal.
- Source :
-
Archives of virology [Arch Virol] 2011 Apr; Vol. 156 (4), pp. 681-4. Date of Electronic Publication: 2011 Feb 06. - Publication Year :
- 2011
-
Abstract
- Rabies is endemic throughout most of Asia, with the majority of human cases transmitted by domestic dogs (Canis familiaris). Here, we report a case of rabies in a 12-year-old girl in the Lalitpur district of Nepal that might have been prevented by better public awareness and timely post-exposure prophylaxis. Molecular characterization of the virus showed 100% identity over a partial nucleoprotein gene sequence to previous isolates from Nepal belonging to the 'arctic-like' lineage of rabies virus. Sequence analysis of both partial nucleoprotein and glycoprotein genes showed differences in consensus sequence after passage in vitro but not after passage in vivo.
Details
- Language :
- English
- ISSN :
- 1432-8798
- Volume :
- 156
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Archives of virology
- Publication Type :
- Academic Journal
- Accession number :
- 21298457
- Full Text :
- https://doi.org/10.1007/s00705-010-0868-9